Adolescence

This project examined the extend to which perspective-taking accounted for the relatoinship between cognitive control and perspective taking as well as the underlying functional brain properties of these assocaitions.

Results from the original data collection (PI Winters) that tested the impact of cognitive control on affective theory of mind in a sample of early adolescents that vary on callous-unemotional traits.

To improve our mechanistic understanding adolescent callous-unemotional traits, we used a novel connectivity method to examine network topology in adolescent brains and how connection density and node centrality was different in the presence of callous-unemotional traits.

This study examined whether the association between transdiagnostic symptoms and suicidality was different in the presence of callous-unemotional traits in a sample of adolescents in substance use treatment.

This study sought to understand how socio-affective functioning may account for the association between the brain and adolescent depression symptoms. We tested this by examining cognitive and affective empathy as indirect effects between brain network connectivity and heterogenous depression symptoms in adolescents.

To understand adolescent brains association with empathy, we examined network level functional connections in adolescent brains that associate with cognitive and affective empathy.

We conducted a meta-analysis of the literature to evaluate the importance of social impairments in substance use disorder as well as recent models that early impairments in socio-cognitive and -affective processes may predict future use.

We used growth curve modeling to examine the impact of empathy’s trajectory on the trajectory of substance use in a sample of adolescents in substance use treatment.

We used growth curve modeling to examine the impact of empathy’s trajectory on the trajectory of substance use in a sample of adolescents in substance use treatment.

Citation: Winters, D. E. (2020). Social Cognitive and Affective Neural Substrates of Adolescent Transdiagnosic Symptoms. Indiana University-Purdue University Indianapolis.