Functional Connectivity

Results from computatoinally simulating lesions acorss the functional connectome to predict CU traits.

This project examined the extend to which perspective-taking accounted for the relatoinship between cognitive control and perspective taking as well as the underlying functional brain properties of these assocaitions.

Callous-unemotional (CU) traits in adolescents are a dimensional construct involving a symptom subset of empathy impairments amongst …

To improve our mechanistic understanding adolescent callous-unemotional traits, we used a novel connectivity method to examine network topology in adolescent brains and how connection density and node centrality was different in the presence of callous-unemotional traits.

This study sought to understand how socio-affective functioning may account for the association between the brain and adolescent depression symptoms. We tested this by examining cognitive and affective empathy as indirect effects between brain network connectivity and heterogenous depression symptoms in adolescents.

To understand adolescent brains association with empathy, we examined network level functional connections in adolescent brains that associate with cognitive and affective empathy.

This project seeks to leverage advanced network connectivity approaches to understand functional brain dynamics underlying socio-affective functioning and antisocial phenotypes from adolescence into adulthood.

This project seeks to test the extent to which cognitive impairments amongst adolescents with callous-unemotional traits drive difficulties to infer and understand others emotions.

This project seeks to determine how distinctions in executive function is implicated in distinct antisocial phenotype symptoms.

Citation: Winters, D. E. (2020). Social Cognitive and Affective Neural Substrates of Adolescent Transdiagnosic Symptoms. Indiana University-Purdue University Indianapolis.